Critical Appraisal Tool Worksheet Example Solution
Critical Appraisal
Critical appraisal is the fourth of the six steps of evidence-based practice to appraise the selected evidence. This critical appraisal serves two main purposes: to assess the evidence for its closeness to the truth or the actual occurrence in the population and to assess the evidence for usefulness in application to practice. My clinical issue of interest was the use of probiotics in the treatment of gastrointestinal symptoms associated with antibiotics use. Eight journal articles from peer-reviewed journals were selected for early steps of critical appraisal. In this critical appraisal, four of the eight articles with varying methodologies and levels of evidence are appraised and evaluated.
Part 3 A: Evaluation Table
| Full APA formatted citation of the selected article. | Article #1 | Article #2 | Article #3 | Article #4 |
| Skrzydto-Radomańska, B., Prozorow-Król, B., Cichoż-Lach, H., Majsiak, E., Bierła, J. B., Kanarek, E., Sowińska, A., &Cukrowska, B. (2021). The effectiveness and safety of multi-strain probiotic preparation in patients with diarrhea-predominant irritable bowel syndrome: A randomized controlled study. Nutrients, 13(3), 756. https://doi.org/10. 3390/nu13030756 |
Hibberd, A. A., Yde, C. C., Ziegler, M. L., Honoré, A. H., Saarinen, M. T., Lahtinen, S., Stahl, B., Jensen, H. M., &Stenman, L. K. (2019). Probiotic or synbiotic alters the gut microbiota and metabolism in a randomized controlled trial of weight management in overweight adults. Beneficial Microbes, 10(2), 121–135. https://doi.org/10. 3920/BM2018.0028 |
Rui, X., & Ma, S.-X. (2020). A retrospective study of probiotics for the treatment of children with antibiotic-associated diarrhea. Medicine, 99(23), e20631. https://doi.org/10.1097/ MD.0000000000020631 |
Arnold, L. E., Luna, R. A., Williams, K., Chan, J., Parker, R. A., Wu, Q., Hollway, J. A., Jeffs, A., Lu, F., Coury, D. L., Hayes, C., &Savidge, T. (2019). Probiotics for gastrointestinal symptoms and quality of life in autism: A placebo-controlled pilot trial. Journal of Child and Adolescent Psychopharmacology, 29(9), 659–669. https://doi.org/10.1089/ cap.2018.0156 |
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| Evidence Level * (I, II, or III) | This is an evidence level I study (Randomized Controlled Study). | The study is evidence Level I (Randomized Controlled Trial). | Evidence Level III (Observational/non-experimental study). | Evidence Level I (A Placebo-Controlled Randomized Pilot Trial). |
| Conceptual Framework Describe the theoretical basis for the study (If there is no one mentioned in the article, say that here).** | The study aimed at determining whether the use of a multi-strain probiotic in adults with irritable bowel syndrome that predominantly presents with diarrhea was effective and safe. | The research purposed to determine if changes in the gut microbiota attributed to probiotic or symbiotic use were associated with the earlier observed clinical benefits of controlling energy metabolism and body fat mass in overweight adult individuals. | The objective of this study was to determine the safety and benefits of probiotics, particularly live combined Bacillus subtilis and Enterococcus faecium granules with multivitamins, when used in the management of children with diarrhea attributed to antibiotics. | The conceptual framework of the research was to analyze gastrointestinal (GI) symptoms in regards to targeted probiotic use with expected effect on the quality of life in autistic spectrum disorders. |
Design/Method Describe the design and how the study was carried out (In detail, includin
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